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The Science Behind NAD+: How It Works in the Body

The Science Behind NAD+: How It Works in the Body

Cellular Longevity: Why Energy Matters for Aging Gracefully

Backed by NAD+ research, Primora fuels your cells to restore energy, enhance resilience, and age on your own terms.

Your body is made up of approximately 37.2 trillion cells, and each one plays a vital role in keeping you alive and functioning. From your brain and heart to your muscles and immune system, cells power every process that sustains your health.

But here’s the catch—cells can’t do their jobs without energy. That energy comes from the mitochondria, tiny organelles inside each cell, often called the powerhouses of life.


Where Cellular Energy Begins: Mitochondria & NAD+

Mitochondria generate about 90% of the body’s energy, converting food into ATP (adenosine triphosphate)—the universal fuel that powers life. This process depends on a steady supply of NAD+ (nicotinamide adenine dinucleotide), a coenzyme essential for mitochondrial function.

Without enough NAD⁺, mitochondria struggle to produce energy, and cells begin to slow down. This cellular energy decline is one of the hallmarks of aging, making NAD⁺ a cornerstone of vitality.


NAD+ for Repair & Regeneration

NAD⁺ does more than fuel energy—it’s also critical for cellular repair and resilience.

Sirtuins, proteins that regulate stress response, inflammation, and DNA stability, require NAD+ to function properly.

PARPs (Poly ADP-ribose polymerases), enzymes that repair DNA damage caused by oxidative stress, also depend on NAD+.

When NAD+ levels are adequate, your cells can repair, regenerate, and withstand daily wear and tear. When they decline, so does your body’s natural ability to recover.


Aging Starts When NAD+ Declines

NAD⁺ levels naturally decline by up to 50% by age 40, and continue dropping with age. Poor sleep, stress, and diet can deplete them even further. At the same time, the body produces fewer new mitochondria, placing extra strain on existing ones.

This combination of reduced energy production and weakened repair capacity is what accelerates aging from the inside out.


Primora's Answer to Cellular Aging

The good news? Cellular vitality can be supported. Lifestyle choices like quality sleep, regular movement, and balanced nutrition are foundational—but supplementation with NAD+ support can take this further.

Primora's clinically crafted NAD⁺ formula is designed to:

Replenish declining NAD+ levels

Boost mitochondrial energy production

Activate sirtuins and repair pathways

Promote healthier, more resilient aging

With our 8-in-1 NAD+ blends, NSF-certified quality standards, and fast-acting bioavailable ingredients, we help you take charge of your energy, clarity, and longevity—starting from the cellular level.

Because longevity isn’t just about living longer.
It’s about living better.


References

Verdin, E. (2015). NAD⁺ in aging, metabolism, and neurodegeneration. Science, 350(6265), 1208–1213.

Rajman, L., Chwalek, K., & Sinclair, D.A. (2018). Therapeutic potential of NAD-boosting molecules: the in vivo evidence. Cell Metabolism, 27(3), 529–547.

Yoshino, J., Baur, J.A., & Imai, S. (2018). NAD⁺ intermediates: The biology and therapeutic potential of NMN and NR. Cell Metabolism, 27(3), 513–528.

Camacho-Pereira, J., et al. (2016). CD38 dictates age-related NAD decline and mitochondrial dysfunction through a SIRT3-dependent mechanism. Cell Metabolism, 23(6), 1127–1139.

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